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Proteinase-Activated Receptor 1 (PAR1) Regulates Leukemic Stem Cell Functions
External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknow...
Autores principales: | Bäumer, Nicole, Krause, Annika, Köhler, Gabriele, Lettermann, Stephanie, Evers, Georg, Hascher, Antje, Bäumer, Sebastian, Berdel, Wolfgang E., Müller-Tidow, Carsten, Tickenbrock, Lara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989293/ https://www.ncbi.nlm.nih.gov/pubmed/24740120 http://dx.doi.org/10.1371/journal.pone.0094993 |
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