Regulation of Insulin Degrading Enzyme Activity by Obesity-Associated Factors and Pioglitazone in Liver of Diet-Induced Obese Mice

Insulin degrading enzyme (IDE) is a potential drug target in the treatment of type 2 diabetes (T2D). IDE controls circulating insulin through a degradation-dependent clearance mechanism in multiple tissues. However, there is not sufficient information about IDE regulation in obesity. In this study,...

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Detalles Bibliográficos
Autores principales: Wei, Xiuqing, Ke, Bilun, Zhao, Zhiyun, Ye, Xin, Gao, Zhanguo, Ye, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989328/
https://www.ncbi.nlm.nih.gov/pubmed/24740421
http://dx.doi.org/10.1371/journal.pone.0095399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989328/
https://www.ncbi.nlm.nih.gov/pubmed/24740421
http://dx.doi.org/10.1371/journal.pone.0095399

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