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Regulation of Insulin Degrading Enzyme Activity by Obesity-Associated Factors and Pioglitazone in Liver of Diet-Induced Obese Mice

Insulin degrading enzyme (IDE) is a potential drug target in the treatment of type 2 diabetes (T2D). IDE controls circulating insulin through a degradation-dependent clearance mechanism in multiple tissues. However, there is not sufficient information about IDE regulation in obesity. In this study,...

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Detalles Bibliográficos
Autores principales:	Wei, Xiuqing, Ke, Bilun, Zhao, Zhiyun, Ye, Xin, Gao, Zhanguo, Ye, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989328/ https://www.ncbi.nlm.nih.gov/pubmed/24740421 http://dx.doi.org/10.1371/journal.pone.0095399

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