Pericentrosomal localization of the TIG3 tumor suppressor requires an N-terminal hydrophilic region motif

TIG3 is a tumor suppressor protein that plays a key role in controlling cell proliferation. TIG3 is observed at reduced levels in epidermal squamous cell carcinoma, and restoration of expression in skin cancer cells reduces cell survival. TIG3 suppresses cell survival via mechanisms that involve loc...

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Detalles Bibliográficos
Autores principales: Scharadin, Tiffany M., Adhikary, Gautam, Shaw, Kristin, Grun, Dan J.B., Xu, Wen, Eckert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989452/
https://www.ncbi.nlm.nih.gov/pubmed/24401997
http://dx.doi.org/10.1038/jid.2013.533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989452/
https://www.ncbi.nlm.nih.gov/pubmed/24401997
http://dx.doi.org/10.1038/jid.2013.533

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