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Cdc42 Inhibits ERK-mediated Collagenase-1 (MMP-1) Expression in Collagen-Activated Human Keratinocytes
Following injury, keratinocytes switch gene expression programs from one that promotes differentiation to one that supports migration. A common feature of human wounds and ulcerations of any form is the expression of MMP-1 (collagenase-1) by leading-edge basal keratinocytes migrating across the derm...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989453/ https://www.ncbi.nlm.nih.gov/pubmed/24352036 http://dx.doi.org/10.1038/jid.2013.499 |