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Cdc42 Inhibits ERK-mediated Collagenase-1 (MMP-1) Expression in Collagen-Activated Human Keratinocytes

Following injury, keratinocytes switch gene expression programs from one that promotes differentiation to one that supports migration. A common feature of human wounds and ulcerations of any form is the expression of MMP-1 (collagenase-1) by leading-edge basal keratinocytes migrating across the derm...

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Detalles Bibliográficos
Autores principales: Rohani, Maryam G., Pilcher, Brian K., Chen, Peter, Parks, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989453/
https://www.ncbi.nlm.nih.gov/pubmed/24352036
http://dx.doi.org/10.1038/jid.2013.499