IL-27, targeting antigen presenting cells, promotes Th17 differentiation and colitis in mice

Th17 cells have been implicated in autoimmunity and inflammatory bowel disease (IBD). Antigen presenting cell (APC) derived cytokines such as IL-1β and IL-6 are key mediators supporting Th17 differentiation, yet how these factors are induced in vivo remains unclear. Here we show that IL-27 acting on...

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Detalles Bibliográficos
Autores principales: Visperas, Anabelle, Do, Jeongsu, Bulek, Katarzyna, Li, Xiaoxia, Min, Booki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989480/
https://www.ncbi.nlm.nih.gov/pubmed/24129161
http://dx.doi.org/10.1038/mi.2013.82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989480/
https://www.ncbi.nlm.nih.gov/pubmed/24129161
http://dx.doi.org/10.1038/mi.2013.82

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