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The fail-safe system to rescue the stalled ribosomes in Escherichia coli

Translation terminates at stop codon. Without stop codon, ribosome cannot terminate translation properly and reaches and stalls at the 3′-end of the mRNA lacking stop codon. Bacterial tmRNA-mediated trans-translation releases such stalled ribosome and targets the protein product to degradation by ad...

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Detalles Bibliográficos
Autores principales: Abo, Tatsuhiko, Chadani, Yuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989581/
https://www.ncbi.nlm.nih.gov/pubmed/24782844
http://dx.doi.org/10.3389/fmicb.2014.00156