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The fail-safe system to rescue the stalled ribosomes in Escherichia coli
Translation terminates at stop codon. Without stop codon, ribosome cannot terminate translation properly and reaches and stalls at the 3′-end of the mRNA lacking stop codon. Bacterial tmRNA-mediated trans-translation releases such stalled ribosome and targets the protein product to degradation by ad...
Autores principales: | Abo, Tatsuhiko, Chadani, Yuhei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989581/ https://www.ncbi.nlm.nih.gov/pubmed/24782844 http://dx.doi.org/10.3389/fmicb.2014.00156 |
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