RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

The sensing of nucleic acids by receptors of the innate immune system is a key component of antimicrobial immunity. RNA:DNA hybrids, as essential intracellular replication intermediates generated during infection, could therefore represent a class of previously uncharacterised pathogen-associated mo...

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Detalles Bibliográficos
Autores principales: Rigby, Rachel E, Webb, Lauren M, Mackenzie, Karen J, Li, Yue, Leitch, Andrea, Reijns, Martin A M, Lundie, Rachel J, Revuelta, Ailsa, Davidson, Donald J, Diebold, Sandra, Modis, Yorgo, MacDonald, Andrew S, Jackson, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989650/
https://www.ncbi.nlm.nih.gov/pubmed/24514026
http://dx.doi.org/10.1002/embj.201386117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989650/
https://www.ncbi.nlm.nih.gov/pubmed/24514026
http://dx.doi.org/10.1002/embj.201386117

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