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Mouse Models to Study Dengue Virus Immunology and Pathogenesis

The development of a compelling murine model of dengue virus (DENV) infection has been challenging, because DENV clinical isolates do not readily replicate or cause pathology in immunocompetent mice. However, research using immunocompromised mice and/or mouse-adapted viruses allows investigation of...

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Detalles Bibliográficos
Autores principales: Zellweger, Raphaël M., Shresta, Sujan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989707/
https://www.ncbi.nlm.nih.gov/pubmed/24782859
http://dx.doi.org/10.3389/fimmu.2014.00151