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Mouse Models to Study Dengue Virus Immunology and Pathogenesis
The development of a compelling murine model of dengue virus (DENV) infection has been challenging, because DENV clinical isolates do not readily replicate or cause pathology in immunocompetent mice. However, research using immunocompromised mice and/or mouse-adapted viruses allows investigation of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989707/ https://www.ncbi.nlm.nih.gov/pubmed/24782859 http://dx.doi.org/10.3389/fimmu.2014.00151 |