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Activation of the γ-Tubulin Complex by the Mto1/2 Complex

The multisubunit γ-tubulin complex (γ-TuC) is critical for microtubule nucleation in eukaryotic cells [1, 2], but it remains unclear how the γ-TuC becomes active specifically at microtubule-organizing centers (MTOCs) and not more broadly throughout the cytoplasm [3, 4]. In the fission yeast Schizosa...

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Detalles Bibliográficos
Autores principales: Lynch, Eric M., Groocock, Lynda M., Borek, Weronika E., Sawin, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989768/
https://www.ncbi.nlm.nih.gov/pubmed/24704079
http://dx.doi.org/10.1016/j.cub.2014.03.006