Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

BACKGROUND: As anti-malarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malaria infections. The US Army is developing tafenoquine (TQ), an analogue of primaquine (PQ), which is expected to be more effective in preventing malaria in deployed milit...

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Detalles Bibliográficos
Autores principales: Li, Qigui, O’Neil, Michael, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Pybus, Brandon, Hickman, Mark, Melendez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989846/
https://www.ncbi.nlm.nih.gov/pubmed/24731238
http://dx.doi.org/10.1186/1475-2875-13-141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989846/
https://www.ncbi.nlm.nih.gov/pubmed/24731238
http://dx.doi.org/10.1186/1475-2875-13-141

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