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Effect of low extracellular pH on NF-κB activation in macrophages()
OBJECTIVE: Many diseases, including atherosclerosis, involve chronic inflammation. The master transcription factor for inflammation is NF-κB. Inflammatory sites have a low extracellular pH. Our objective was to demonstrate the effect of pH on NF-κB activation and cytokine secretion. METHODS: Mouse J...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989994/ https://www.ncbi.nlm.nih.gov/pubmed/24530961 http://dx.doi.org/10.1016/j.atherosclerosis.2014.01.014 |