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Effect of low extracellular pH on NF-κB activation in macrophages()

OBJECTIVE: Many diseases, including atherosclerosis, involve chronic inflammation. The master transcription factor for inflammation is NF-κB. Inflammatory sites have a low extracellular pH. Our objective was to demonstrate the effect of pH on NF-κB activation and cytokine secretion. METHODS: Mouse J...

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Detalles Bibliográficos
Autores principales: Gerry, A.B., Leake, D.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989994/
https://www.ncbi.nlm.nih.gov/pubmed/24530961
http://dx.doi.org/10.1016/j.atherosclerosis.2014.01.014