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The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development()
We hypothesise that intraerythrocytic malaria parasite metabolism is not merely fulfilling the need for ATP generation, but is evolved to support rapid proliferation, similar to that seen in other rapidly proliferating cells such as cancer cells. Deregulated glycolytic activity coupled with impaired...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989997/ https://www.ncbi.nlm.nih.gov/pubmed/24636355 http://dx.doi.org/10.1016/j.pt.2014.02.001 |