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High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons

In the mammalian brain, the neurotrophin brain-derived neurotrophic factor (BDNF) has emerged as a key factor for synaptic refinement, plasticity and learning. Although BDNF-induced signaling cascades are well known, the spatial aspects of the synaptic BDNF localization remained unclear. Recent data...

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Detalles Bibliográficos
Autores principales: Andreska, Thomas, Aufmkolk, Sarah, Sauer, Markus, Blum, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990111/
https://www.ncbi.nlm.nih.gov/pubmed/24782711
http://dx.doi.org/10.3389/fncel.2014.00107