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Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?

A significant proportion (up to 62%) of oral squamous cell carcinomas (OSCCs) may arise from oral potential malignant lesions (OPMLs), such as leukoplakia. Patient outcomes may thus be improved through detection of lesions at a risk for malignant transformation, by identifying and categorizing genet...

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Detalles Bibliográficos
Autores principales: Cervigne, Nilva K., Machado, Jerry, Goswami, Rashmi S., Sadikovic, Bekim, Bradley, Grace, Perez-Ordonez, Bayardo, Galloni, Natalie Naranjo, Gilbert, Ralph, Gullane, Patrick, Irish, Jonathan C., Jurisica, Igor, Reis, Patricia P., Kamel-Reid, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990162/
https://www.ncbi.nlm.nih.gov/pubmed/24403051
http://dx.doi.org/10.1093/hmg/ddt657