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Effect of hypoxia on the expression of αB-crystallin in head and neck squamous cell carcinoma

BACKGROUND: The presence of hypoxia in head and neck squamous cell carcinoma (HNSCC) is associated with therapeutic resistance and increased risk of metastasis formation. αB-crystallin (HspB5) is a small heat shock protein, which is also associated with metastasis formation in HNSCC. In this study,...

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Detalles Bibliográficos
Autores principales: van de Schootbrugge, Chantal, Schults, Elisabeth MJ, Bussink, Johan, Span, Paul N, Grénman, Reidar, Pruijn, Ger JM, Kaanders, Johannes HAM, Boelens, Wilbert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990244/
https://www.ncbi.nlm.nih.gov/pubmed/24725344
http://dx.doi.org/10.1186/1471-2407-14-252