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Pharmacokinetics of Zidovudine Dosed Twice Daily According to World Health Organization Weight Bands in Ugandan HIV-infected Children

Data on zidovudine pharmacokinetics in children dosed using World Health Organization weight bands are limited. About 45 HIV-infected, Ugandan children, 3.4 (2.6–6.2) years, had intensive pharmacokinetic sampling. Geometric mean zidovudine AUC(0–12h) was 3.0 h.mg/L, which is higher than previously o...

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Detalles Bibliográficos
Autores principales: Fillekes, Quirine, Kendall, Lindsay, Kitaka, Sabrina, Mugyenyi, Peter, Musoke, Philippa, Ndigendawani, Milly, Bwakura-Dangarembizi, Mutsa, Gibb, Diana M., Burger, David, Walker, Ann Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990384/
https://www.ncbi.nlm.nih.gov/pubmed/24736440
http://dx.doi.org/10.1097/INF.0000000000000143