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Molecular mechanism and physiological role of active–deactive transition of mitochondrial complex I
The unique feature of mitochondrial complex I is the so-called A/D transition (active–deactive transition). The A-form catalyses rapid oxidation of NADH by ubiquinone (k ~10(4) min(−1)) and spontaneously converts into the D-form if the enzyme is idle at physiological temperatures. Such deactivation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990385/ https://www.ncbi.nlm.nih.gov/pubmed/24059527 http://dx.doi.org/10.1042/BST20130088 |