The Missense of Smell: Functional Variability in the Human Odorant Receptor Repertoire

Humans have approximately 400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function. We identified ago...

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Detalles Bibliográficos
Autores principales: Mainland, Joel D., Keller, Andreas, Li, Yun R., Zhou, Ting, Trimmer, Casey, Snyder, Lindsey L., Moberly, Andrew H., Adipietro, Kaylin A., Liu, Wen Ling L., Zhuang, Hanyi, Zhan, Senmiao, Lee, Somin S., Lin, Abigail, Matsunami, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990440/
https://www.ncbi.nlm.nih.gov/pubmed/24316890
http://dx.doi.org/10.1038/nn.3598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990440/
https://www.ncbi.nlm.nih.gov/pubmed/24316890
http://dx.doi.org/10.1038/nn.3598

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