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Impact of Different Oseltamivir Regimens on Treating Influenza A Virus Infection and Resistance Emergence: Insights from a Modelling Study

Several studies have proven oseltamivir to be efficient in reducing influenza viral titer and symptom intensity. However, the usefulness of oseltamivir can be compromised by the emergence and spread of drug-resistant virus. The selective pressure exerted by different oseltamivir therapy regimens hav...

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Detalles Bibliográficos
Autores principales: Canini, Laetitia, Conway, Jessica M., Perelson, Alan S., Carrat, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990489/
https://www.ncbi.nlm.nih.gov/pubmed/24743564
http://dx.doi.org/10.1371/journal.pcbi.1003568