Foxm1 Mediates LIF/Stat3-Dependent Self-Renewal in Mouse Embryonic Stem Cells and Is Essential for the Generation of Induced Pluripotent Stem Cells

Activation of signal transducer and activator of transcription 3 (Stat3) by leukemia inhibitory factor (LIF) is required for maintaining self-renewal and pluripotency of mouse embryonic stem cells (mESCs). Here, we have confirmed transcription factor Forkhead Box m1 (Foxm1) as a LIF/Stat3 downstream...

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Detalles Bibliográficos
Autores principales: Tan, Guixiang, Cheng, Liang, Chen, Tuanhui, Yu, Li, Tan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990529/
https://www.ncbi.nlm.nih.gov/pubmed/24743237
http://dx.doi.org/10.1371/journal.pone.0092304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990529/
https://www.ncbi.nlm.nih.gov/pubmed/24743237
http://dx.doi.org/10.1371/journal.pone.0092304

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