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Functional Substitution of a Eukaryotic Glycyl-tRNA Synthetase with an Evolutionarily Unrelated Bacterial Cognate Enzyme

Two oligomeric types of glycyl-tRNA synthetase (GlyRS) are found in nature: a α(2) type and a α(2)β(2) type. The former has been identified in all three kingdoms of life and often pairs with tRNA(Gly) that carries an A73 discriminator base, while the latter is found only in bacteria and chloroplasts...

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Detalles Bibliográficos
Autores principales: Chien, Chin-I, Chen, Yu-Wei, Wu, Yi-Hua, Chang, Chih-Yao, Wang, Tzu-Ling, Wang, Chien-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990555/
https://www.ncbi.nlm.nih.gov/pubmed/24743154
http://dx.doi.org/10.1371/journal.pone.0094659