Genetic Variants in FBN-1 and Risk for Thoracic Aortic Aneurysm and Dissection

OBJECTIVES: A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD), non-dissecting thoracic aortic aneurysm (TAA),...

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Detalles Bibliográficos
Autores principales: Iakoubova, Olga A., Tong, Carmen H., Rowland, Charles M., Luke, May M., Garcia, Veronica E., Catanese, Joseph J., Moomiaie, Remo M., Sotonyi, Peter, Ascady, Gyorgy, Nikas, Demitrios, Dedelias, Panagiotis, Tranquilli, Maryann, Elefteriades, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990573/
https://www.ncbi.nlm.nih.gov/pubmed/24743685
http://dx.doi.org/10.1371/journal.pone.0091437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990573/
https://www.ncbi.nlm.nih.gov/pubmed/24743685
http://dx.doi.org/10.1371/journal.pone.0091437

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