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The CpG Island Encompassing the Promoter and First Exon of Human DNMT3L Gene Is a PcG/TrX Response Element (PRE)

DNMT3L, a member of DNA methyltransferases family, is present only in mammals. As it provides specificity to the action of de novo methyltransferases, DNMT3A and DNMT3B and interacts with histone H3, DNMT3L has been invoked as the molecule that can read the histone code and translate it into DNA met...

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Detalles Bibliográficos
Autores principales: Basu, Amitava, Dasari, Vasanthi, Mishra, Rakesh K., Khosla, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990577/
https://www.ncbi.nlm.nih.gov/pubmed/24743422
http://dx.doi.org/10.1371/journal.pone.0093561