Single Cell Analysis Reveals the Stochastic Phase of Reprogramming to Pluripotency Is an Ordered Probabilistic Process

Despite years of research, the reprogramming of human somatic cells to pluripotency remains a slow, inefficient process, and a detailed mechanistic understanding of reprogramming remains elusive. Current models suggest reprogramming to pluripotency occurs in two-phases: a prolonged stochastic phase...

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Detalles Bibliográficos
Autores principales: Chung, Kyung-Min, Kolling IV, Frederick W., Gajdosik, Matthew D., Burger, Steven, Russell, Alexander C., Nelson, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990627/
https://www.ncbi.nlm.nih.gov/pubmed/24743916
http://dx.doi.org/10.1371/journal.pone.0095304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990627/
https://www.ncbi.nlm.nih.gov/pubmed/24743916
http://dx.doi.org/10.1371/journal.pone.0095304

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