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Identification of Verrucarin A as a Potent and Selective Steroid Receptor Coactivator-3 Small Molecule Inhibitor

Members of the steroid receptor coactivator (SRC) family are overexpressed in numerous types of cancers. In particular, steroid receptor coactivator 3 (SRC-3) has been recognized as a critical coactivator associated with tumor initiation, progression, recurrence, metastasis, and chemoresistance wher...

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Detalles Bibliográficos
Autores principales: Yan, Fei, Yu, Yang, Chow, Dar-Chone, Palzkill, Timothy, Madoux, Franck, Hodder, Peter, Chase, Peter, Griffin, Patrick R., O'Malley, Bert W., Lonard, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990629/
https://www.ncbi.nlm.nih.gov/pubmed/24743578
http://dx.doi.org/10.1371/journal.pone.0095243