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Downregulation of Complement C3 and C3aR Expression in Subcutaneous Adipose Tissue in Obese Women

BACKGROUND: The central component of the complement system, C3, is associated with obesity, metabolic syndrome and cardiovascular disease however the underlying reasons are unknown. In the present study we evaluated gene expression of C3, the cleavage product C3a/C3adesArg and its cognate receptor C...

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Detalles Bibliográficos
Autores principales: Gupta, Abhishek, Rezvani, Reza, Lapointe, Marc, Poursharifi, Pegah, Marceau, Picard, Tiwari, Sunita, Tchernof, Andre, Cianflone, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990631/
https://www.ncbi.nlm.nih.gov/pubmed/24743347
http://dx.doi.org/10.1371/journal.pone.0095478