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Regulator of G Protein Signaling 2 (RGS2) and RGS4 Form Distinct G Protein-Dependent Complexes with Protease Activated-Receptor 1 (PAR1) in Live Cells
Protease-activated receptor 1 (PAR1) is a G-protein coupled receptor (GPCR) that is activated by natural proteases to regulate many physiological actions. We previously reported that PAR1 couples to G(i), G(q) and G(12) to activate linked signaling pathways. Regulators of G protein signaling (RGS) p...
Autores principales: | Ghil, Sungho, McCoy, Kelly L., Hepler, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990635/ https://www.ncbi.nlm.nih.gov/pubmed/24743392 http://dx.doi.org/10.1371/journal.pone.0095355 |
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