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Development of a Chemically Defined Medium and Discovery of New Mitogenic Growth Factors for Mouse Hepatocytes: Mitogenic Effects of FGF1/2 and PDGF

Chemically defined serum-free media for rat hepatocytes have been useful in identifying EGFR ligands and HGF/MET signaling as direct mitogenic factors for rat hepatocytes. The absence of such media for mouse hepatocytes has prevented screening for discovery of such mitogens for mouse hepatocytes. We...

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Detalles Bibliográficos
Autores principales: Bowen, William C., Michalopoulos, Amantha W., Orr, Anne, Ding, Michael Q., Stolz, Donna B., Michalopoulos, George K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990636/
https://www.ncbi.nlm.nih.gov/pubmed/24743506
http://dx.doi.org/10.1371/journal.pone.0095487