SRA Regulates Adipogenesis by Modulating p38/JNK Phosphorylation and Stimulating Insulin Receptor Gene Expression and Downstream Signaling

The Steroid Receptor RNA Activator (SRA) enhances adipogenesis and increases both glucose uptake and phosphorylation of Akt and FOXO1 in response to insulin. To assess the mechanism, we differentiated ST2 mesenchymal precursor cells that did or did not overexpress SRA into adipocytes using combinati...

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Detalles Bibliográficos
Autores principales: Liu, Shannon, Xu, Ruichuan, Gerin, Isabelle, Cawthorn, William P., MacDougald, Ormond A., Chen, Xiao-Wei, Saltiel, Alan R., Koenig, Ronald J., Xu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990642/
https://www.ncbi.nlm.nih.gov/pubmed/24743795
http://dx.doi.org/10.1371/journal.pone.0095416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990642/
https://www.ncbi.nlm.nih.gov/pubmed/24743795
http://dx.doi.org/10.1371/journal.pone.0095416

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