Low-Dose Levodopa Protects Nerve Cells from Oxidative Stress and Up-Regulates Expression of pCREB and CD39

OBJECTIVE: This study aimed to investigate the influence of low-dose levodopa (L-DOPA) on neuronal cell death under oxidative stress. METHODS: PC12 cells were treated with L-DOPA at different concentrations. We detected the L-DOPA induced reactive oxygen species (ROS). Meanwhile, MTT and LDH assay w...

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Detalles Bibliográficos
Autores principales: Zhong, Shi-Ying, Chen, Yong-Xing, Fang, Min, Zhu, Xiao-Long, Zhao, Yan-Xin, Liu, Xue-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990701/
https://www.ncbi.nlm.nih.gov/pubmed/24743653
http://dx.doi.org/10.1371/journal.pone.0095387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990701/
https://www.ncbi.nlm.nih.gov/pubmed/24743653
http://dx.doi.org/10.1371/journal.pone.0095387

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