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Low-Dose Levodopa Protects Nerve Cells from Oxidative Stress and Up-Regulates Expression of pCREB and CD39
OBJECTIVE: This study aimed to investigate the influence of low-dose levodopa (L-DOPA) on neuronal cell death under oxidative stress. METHODS: PC12 cells were treated with L-DOPA at different concentrations. We detected the L-DOPA induced reactive oxygen species (ROS). Meanwhile, MTT and LDH assay w...
Autores principales: | Zhong, Shi-Ying, Chen, Yong-Xing, Fang, Min, Zhu, Xiao-Long, Zhao, Yan-Xin, Liu, Xue-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990701/ https://www.ncbi.nlm.nih.gov/pubmed/24743653 http://dx.doi.org/10.1371/journal.pone.0095387 |
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