Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

Modified vaccinia virus Ankara (MVA) is an attenuated poxvirus that has been engineered as a vaccine against infectious agents and cancers. Our goal is to understand how MVA modulates innate immunity in dendritic cells (DCs), which can provide insights to vaccine design. In this study, using murine...

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Detalles Bibliográficos
Autores principales: Dai, Peihong, Wang, Weiyi, Cao, Hua, Avogadri, Francesca, Dai, Lianpan, Drexler, Ingo, Joyce, Johanna A., Li, Xiao-Dong, Chen, Zhijian, Merghoub, Taha, Shuman, Stewart, Deng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990710/
https://www.ncbi.nlm.nih.gov/pubmed/24743339
http://dx.doi.org/10.1371/journal.ppat.1003989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990710/
https://www.ncbi.nlm.nih.gov/pubmed/24743339
http://dx.doi.org/10.1371/journal.ppat.1003989

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