TCR Affinity Associated with Functional Differences between Dominant and Subdominant SIV Epitope-Specific CD8(+) T Cells in Mamu-A*01 (+) Rhesus Monkeys

Many of the factors that contribute to CD8(+) T cell immunodominance hierarchies during viral infection are known. However, the functional differences that exist between dominant and subdominant epitope-specific CD8(+) T cells remain poorly understood. In this study, we characterized the phenotypic...

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Detalles Bibliográficos
Autores principales: Osuna, Christa E., Gonzalez, Ana Maria, Chang, Hsun-Hsien, Hung, Amy Shi, Ehlinger, Elizabeth, Anasti, Kara, Alam, S. Munir, Letvin, Norman L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990730/
https://www.ncbi.nlm.nih.gov/pubmed/24743648
http://dx.doi.org/10.1371/journal.ppat.1004069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990730/
https://www.ncbi.nlm.nih.gov/pubmed/24743648
http://dx.doi.org/10.1371/journal.ppat.1004069

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