Cargando…

TCR Affinity Associated with Functional Differences between Dominant and Subdominant SIV Epitope-Specific CD8(+) T Cells in Mamu-A*01 (+) Rhesus Monkeys

Many of the factors that contribute to CD8(+) T cell immunodominance hierarchies during viral infection are known. However, the functional differences that exist between dominant and subdominant epitope-specific CD8(+) T cells remain poorly understood. In this study, we characterized the phenotypic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Osuna, Christa E., Gonzalez, Ana Maria, Chang, Hsun-Hsien, Hung, Amy Shi, Ehlinger, Elizabeth, Anasti, Kara, Alam, S. Munir, Letvin, Norman L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990730/ https://www.ncbi.nlm.nih.gov/pubmed/24743648 http://dx.doi.org/10.1371/journal.ppat.1004069

Ejemplares similares

Contributions of Mamu-A*01 Status and TRIM5 Allele Expression, But Not CCL3L Copy Number Variation, to the Control of SIVmac251 Replication in Indian-Origin Rhesus Monkeys
por: Lim, So-Yon, et al.
Publicado: (2010)

SIVΔnef vaccination mobilizes systemic and mucosal natural killer cells in Mamu A*01+ macaques
por: Reeves, R, et al.
Publicado: (2012)

Association of Activating KIR Copy Number Variation of NK Cells with Containment of SIV Replication in Rhesus Monkeys
por: Hellmann, Ina, et al.
Publicado: (2011)

Correction: Association of Activating KIR Copy Number Variation of NK Cells with Containment of SIV Replication in Rhesus Monkeys
por: Hellmann, Ina, et al.
Publicado: (2012)

MamuSNP: A Resource for Rhesus Macaque (Macaca mulatta) Genomics
por: Malhi, Ripan S., et al.
Publicado: (2007)

CD8(+) T Cells from SIV Elite Controller Macaques Recognize Mamu-B*08-Bound Epitopes and Select for Widespread Viral Variation
por: Loffredo, John T., et al.
Publicado: (2007)

A snapshot of the Mamu-B genes and their allelic repertoire in rhesus macaques of Chinese origin
por: Otting, Nel, et al.
Publicado: (2008)

P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys
por: Basavapathruni, A, et al.
Publicado: (2009)

Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death
por: Rogers, Thomas F, et al.
Publicado: (2010)

Virus-specific cellular immune correlates of survival in vaccinated monkeys after SIV challenge
por: Letvin, Norman
Publicado: (2006)

Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys
por: Whitney, James B., et al.
Publicado: (2014)

Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys
por: Boopathy, Archana V., et al.
Publicado: (2023)

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2011)

A Coarse-Grained Model of Affinity Maturation Indicates the Importance of B-Cell Receptor Avidity in Epitope Subdominance
por: Ovchinnikov, Victor, et al.
Publicado: (2022)

Spontaneous endometriosis in rhesus macaques: evidence for a genetic association with specific Mamu-A1 alleles
por: Kondova, Ivanela, et al.
Publicado: (2017)

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2018)

P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys
por: Yeh, WW, et al.
Publicado: (2009)

Immune Control of an SIV Challenge by a T Cell-Based Vaccine in Rhesus Monkeys
por: Liu, Jinyan, et al.
Publicado: (2008)

Vaccine Protection Against Acquisition of Neutralization-Resistant SIV Challenges in Rhesus Monkeys
por: Barouch, Dan H., et al.
Publicado: (2012)

SIV infection aggravates malaria in a Chinese rhesus monkey coinfection model
por: Liu, Guangjie, et al.
Publicado: (2019)

Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine
por: Schwerdtfeger, Melanie, et al.
Publicado: (2019)

P19-57 LB. Gene-based vaccination protects against mucosal infection by a heterologous highly pathogenic SIV isolate in rhesus monkeys
por: Letvin, N, et al.
Publicado: (2009)

Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys
por: Kaur, Amitinder, et al.
Publicado: (2018)

Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys
por: Pan, Enxiang, et al.
Publicado: (2018)

Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
por: Liu, Po-Ting, et al.
Publicado: (2020)

Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities
por: Southwood, Scott, et al.
Publicado: (2011)

Immunodominant Cytomegalovirus Epitopes Suppress Subdominant Epitopes in the Generation of High-Avidity CD8 T Cells
por: Freitag, Kirsten, et al.
Publicado: (2021)

Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge
por: Hansen, Scott G., et al.
Publicado: (2009)

Accelerated heterologous prime-boost adenovirus vector-based SIV vaccine in neonatal rhesus monkeys
por: Liu, J, et al.
Publicado: (2012)

Immune control of an SIV challenge by a heterolgous and direct mucosal vaccination regimen in rhesus monkeys
por: Sun, C, et al.
Publicado: (2012)

Ad26/MVA Therapeutic Vaccination with TLR7 Stimulation in SIV-Infected Rhesus Monkeys
por: Borducchi, Erica N., et al.
Publicado: (2016)

TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys
por: Lim, So-Yon, et al.
Publicado: (2010)

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
por: Sesterhenn, Fabian, et al.
Publicado: (2019)

Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques
por: Hu, Xintao, et al.
Publicado: (2018)

P19-38. Safety and protective immunity in Rhesus monkeys immunized with replication-defective HIV/SIV vaccine
por: Tung, F, et al.
Publicado: (2009)

ATM-TCR: TCR-Epitope Binding Affinity Prediction Using a Multi-Head Self-Attention Model
por: Cai, Michael, et al.
Publicado: (2022)

Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication
por: Xu, Huanbin, et al.
Publicado: (2017)

Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes
por: Silva, Murillo, et al.
Publicado: (2017)

P17-24. Interfering overlapping epitopes contribute to the subdominance of an HLA-A2-restricted HIV Gag-specific epitope
por: Kan-Mitchell, J, et al.
Publicado: (2009)

Epitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice
por: Mitchell, Daniel A. J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ih7t13r093pt79ocvpqc93pcgo