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Production of Apolipoprotein C-III Knockout Rabbits using Zinc Finger Nucleases

Apolipoprotein (Apo) C-III (ApoCIII) resides on the surface of plasma chylomicron (CM), very low density lipoprotein (VLDL) and high density lipoproteins (HDL). It has been recognized that high levels of plasma ApoCIII constitutea risk factor for cardiovascular diseases (CVD). Elevated plasma ApoCII...

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Detalles Bibliográficos
Autores principales: Yang, Dongshan, Zhang, Jifeng, Xu, Jie, Zhu, Tianqing, Fan, Yanbo, Fan, Jianglin, Chen, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991373/
https://www.ncbi.nlm.nih.gov/pubmed/24301055
http://dx.doi.org/10.3791/50957