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Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

Transformation of pluripotent epiblast cells into a cup-shaped epithelium as the mouse blastocyst implants is a poorly understood and yet key developmental step. Studies of morphogenesis in embryoid bodies led to the current belief that it is programmed cell death that shapes the epiblast. However,...

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Detalles Bibliográficos
Autores principales: Bedzhov, Ivan, Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991392/
https://www.ncbi.nlm.nih.gov/pubmed/24529478
http://dx.doi.org/10.1016/j.cell.2014.01.023