Cargando…

SUMO Chain-Induced Dimerization Activates RNF4

Dimeric RING E3 ligases interact with protein substrates and conformationally restrain the ubiquitin-E2-conjugating enzyme thioester complex such that it is primed for catalysis. RNF4 is an E3 ligase containing an N-terminal domain that binds its polySUMO substrates and a C-terminal RING domain resp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rojas-Fernandez, Alejandro, Plechanovová, Anna, Hattersley, Neil, Jaffray, Ellis, Tatham, Michael H., Hay, Ronald T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991395/ https://www.ncbi.nlm.nih.gov/pubmed/24656128 http://dx.doi.org/10.1016/j.molcel.2014.02.031

Ejemplares similares

Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4
por: Xu, Yingqi, et al.
Publicado: (2014)

Arsenic-Induced SUMO-Dependent Recruitment of RNF4 into PML Nuclear Bodies
por: Geoffroy, Marie-Claude, et al.
Publicado: (2010)

The SUMO protease SENP6 is a direct regulator of PML nuclear bodies
por: Hattersley, Neil, et al.
Publicado: (2011)

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
por: Plechanovová, Anna, et al.
Publicado: (2012)

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini
por: Tatham, Michael H., et al.
Publicado: (2013)

Structural basis for the RING catalyzed synthesis of K63 linked ubiquitin chains
por: Branigan, Emma, et al.
Publicado: (2015)

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA
por: Jaffray, Ellis G., et al.
Publicado: (2023)

Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage
por: Maure, Jean-François, et al.
Publicado: (2016)

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain
por: Sriramachandran, Annie M., et al.
Publicado: (2019)

A SUMO-Dependent Protein Network Regulates Chromosome Congression during Oocyte Meiosis
por: Pelisch, Federico, et al.
Publicado: (2017)

Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway
por: Liu, Julio C Y, et al.
Publicado: (2021)

Identification of SUMO Targets Associated With the Pluripotent State in Human Stem Cells
por: Mojsa, Barbara, et al.
Publicado: (2021)

Analysis of the SUMO2 Proteome during HSV-1 Infection
por: Sloan, Elizabeth, et al.
Publicado: (2015)

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α
por: van Hagen, Martijn, et al.
Publicado: (2010)

Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer
por: Murphy, Paul, et al.
Publicado: (2020)

Requirement of PML SUMO Interacting Motif for RNF4- or Arsenic Trioxide-Induced Degradation of Nuclear PML Isoforms
por: Maroui, Mohamed Ali, et al.
Publicado: (2012)

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery
por: Kumar, Ramesh, et al.
Publicado: (2017)

Absolute SILAC-Compatible Expression Strain Allows Sumo-2 Copy Number Determination in Clinical Samples
por: Matic, Ivan, et al.
Publicado: (2011)

The SUMO-targeted ubiquitin ligase RNF4 regulates localization and function of the HTLV-1 oncoprotein Tax
por: Fryrear, Kimberly A, et al.
Publicado: (2011)

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity
por: Schmidt, Nora, et al.
Publicado: (2019)

SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models
por: Marinello, Martina, et al.
Publicado: (2019)

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination
por: Qiao, Huanyu, et al.
Publicado: (2014)

HTLV-1 Tax binds to and stabilizes the SUMO-targeted ubiquitin ligase RNF4 during DNA damage response
por: Guo, Xin, et al.
Publicado: (2014)

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
por: Poulsen, Sara L., et al.
Publicado: (2013)

Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO
por: Keusekotten, Kirstin, et al.
Publicado: (2013)

A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity
por: Iyer, R. Sumanth, et al.
Publicado: (2017)

SUMOylation of the GTPase Rac1 is required for optimal cell migration
por: Castillo-Lluva, Sonia, et al.
Publicado: (2010)

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2
por: Mo, Yongzhen, et al.
Publicado: (2021)

SUMO Chains Rule on Chromatin Occupancy
por: Keiten-Schmitz, Jan, et al.
Publicado: (2020)

Expanding SUMO and ubiquitin-mediated signaling through hybrid SUMO-ubiquitin chains and their receptors
por: Guzzo, Catherine M., et al.
Publicado: (2013)

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
por: Danielsen, Jannie Rendtlew, et al.
Publicado: (2012)

Evolution of SUMO Function and Chain Formation in Insects
por: Ureña, Enric, et al.
Publicado: (2016)

Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4
por: Pfeiffer, Annika, et al.
Publicado: (2017)

Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1
por: De La Cruz-Herrera, Carlos F., et al.
Publicado: (2023)

SUMO chain formation relies on the amino-terminal region of SUMO-conjugating enzyme and has dedicated substrates in plants
por: Tomanov, Konstantin, et al.
Publicado: (2018)

Cytokine-Induced Nuclear Factor Kappa B Activation Promotes the Survival of Developing Neurons
por: Middleton, Gayle, et al.
Publicado: (2000)

Sumoylation regulates protein dynamics during meiotic chromosome segregation in C. elegans oocytes
por: Pelisch, Federico, et al.
Publicado: (2019)

SUMO Chain Formation Is Required for Response to Replication Arrest in S. pombe
por: Skilton, Andrew, et al.
Publicado: (2009)

The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus
por: Li, Jinlin, et al.
Publicado: (2017)

Total Chemical Synthesis of SUMO and SUMO‐Based Probes for Profiling the Activity of SUMO‐Specific Proteases
por: Mulder, Monique P. C., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3ju3hrfj83rdjj9cmh25i7lups