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Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling

Ischemia-reperfusion (I/R) often leads to acute kidney injury, chronic renal failure and kidney transplantation failure. Glycyrrhizin is extracted from Glycyrrhiza glabra roots and is the predominant active component, which exhibits anti-inflammatory effects. However, to the best of our knowledge, t...

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Detalles Bibliográficos
Autores principales: YE, SHAOJUN, ZHU, YI, MING, YINGZI, SHE, XINGGUO, LIU, HONG, YE, QIFA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991492/
https://www.ncbi.nlm.nih.gov/pubmed/24940420
http://dx.doi.org/10.3892/etm.2014.1570