DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line

This study used the MG-63 osteosarcoma cell line to investigate the demethylation of the phosphate and tension homolog (PTEN) gene promoter and the change in PTEN gene expression levels, which are caused by the methylation inhibitor 5-azacytidine (5-Zac), and the association between the two. Differe...

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Detalles Bibliográficos
Autores principales: SONG, DEYE, NI, JIANGDONG, XIE, HONGMING, DING, MULIANG, WANG, JUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991544/
https://www.ncbi.nlm.nih.gov/pubmed/24940389
http://dx.doi.org/10.3892/etm.2014.1571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991544/
https://www.ncbi.nlm.nih.gov/pubmed/24940389
http://dx.doi.org/10.3892/etm.2014.1571

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