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Increased P16 DNA Methylation in Mouse Thymic Lymphoma Induced by Irradiation
DNA methylation is an important part of epigenetics. In this study, we examined the methylation state of two CpG islands in the promoter of the p16 gene in radiation-induced thymic lymphoma samples. The mRNA and protein levels of P16 were significantly reduced in radiation-induced thymic lymphoma ti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991568/ https://www.ncbi.nlm.nih.gov/pubmed/24747802 http://dx.doi.org/10.1371/journal.pone.0093850 |