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Increased P16 DNA Methylation in Mouse Thymic Lymphoma Induced by Irradiation

DNA methylation is an important part of epigenetics. In this study, we examined the methylation state of two CpG islands in the promoter of the p16 gene in radiation-induced thymic lymphoma samples. The mRNA and protein levels of P16 were significantly reduced in radiation-induced thymic lymphoma ti...

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Detalles Bibliográficos
Autores principales: Song, Wengang, Liu, Yongzhe, Liu, Ying, Zhang, Cong, Yuan, Bao, Zhang, Lianbo, Sun, Shilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991568/
https://www.ncbi.nlm.nih.gov/pubmed/24747802
http://dx.doi.org/10.1371/journal.pone.0093850

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