Structural basis for translocation by AddAB helicase/nuclease and its arrest at Chi sites

In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is dependent upon the recombination hotspot sequence Chi(1,2) and is catalysed by either an AddAB or RecBCD-type helicase-nuclease (reviewed in refs 3, 4). These enzyme complexes unwind and digest the...

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Detalles Bibliográficos
Autores principales: Krajewski, Wojciech W., Fu, Xin, Wilkinson, Martin, Cronin, Nora B., Dillingham, Mark S., Wigley, Dale B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991583/
https://www.ncbi.nlm.nih.gov/pubmed/24670664
http://dx.doi.org/10.1038/nature13037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991583/
https://www.ncbi.nlm.nih.gov/pubmed/24670664
http://dx.doi.org/10.1038/nature13037

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