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Structural basis for translocation by AddAB helicase/nuclease and its arrest at Chi sites

In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is dependent upon the recombination hotspot sequence Chi(1,2) and is catalysed by either an AddAB or RecBCD-type helicase-nuclease (reviewed in refs 3, 4). These enzyme complexes unwind and digest the...

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Detalles Bibliográficos
Autores principales:	Krajewski, Wojciech W., Fu, Xin, Wilkinson, Martin, Cronin, Nora B., Dillingham, Mark S., Wigley, Dale B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991583/ https://www.ncbi.nlm.nih.gov/pubmed/24670664 http://dx.doi.org/10.1038/nature13037

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