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Targeting NAD(+) Metabolism in the Human Malaria Parasite Plasmodium falciparum

Nicotinamide adenine dinucleotide (NAD(+)) is an essential metabolite utilized as a redox cofactor and enzyme substrate in numerous cellular processes. Elevated NAD(+) levels have been observed in red blood cells infected with the malaria parasite Plasmodium falciparum, but little is known regarding...

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Detalles Bibliográficos
Autores principales: O'Hara, Jessica K., Kerwin, Lewis J., Cobbold, Simon A., Tai, Jonathan, Bedell, Thomas A., Reider, Paul J., Llinás, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991606/
https://www.ncbi.nlm.nih.gov/pubmed/24747974
http://dx.doi.org/10.1371/journal.pone.0094061