Immobilised Histidine Tagged β (2)-Adrenoceptor Oriented by a Diazonium Salt Reaction and Its Application in Exploring Drug-Protein Interaction Using Ephedrine and Pseudoephedrine as Probes

A new oriented method using a diazonium salt reaction was developed for linking β (2)-adrenoceptor (β (2)-AR) on the surface of macroporous silica gel. Stationary phase containing the immobilised receptor was used to investigate the interaction between β (2)-AR and ephedrine plus pseudoephedrine by...

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Detalles Bibliográficos
Autores principales: Li, Qian, Bian, Liujiao, Zhao, Xinfeng, Gao, Xiaokang, Zheng, Jianbin, Li, Zijian, Zhang, Youyi, Jiang, Ru, Zheng, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991622/
https://www.ncbi.nlm.nih.gov/pubmed/24747442
http://dx.doi.org/10.1371/journal.pone.0094955

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