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RyR2 Modulates a Ca(2+)-Activated K(+) Current in Mouse Cardiac Myocytes

In cardiomyocytes, Ca(2+) entry through voltage-dependent Ca(2+) channels (VDCCs) binds to and activates RyR2 channels, resulting in subsequent Ca(2+) release from the sarcoplasmic reticulum (SR) and cardiac contraction. Previous research has documented the molecular coupling of small-conductance Ca...

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Detalles Bibliográficos
Autores principales: Mu, Yong-hui, Zhao, Wen-chao, Duan, Ping, Chen, Yun, Zhao, Wei-da, Wang, Qian, Tu, Hui-yin, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991633/
https://www.ncbi.nlm.nih.gov/pubmed/24747296
http://dx.doi.org/10.1371/journal.pone.0094905