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HIV-1 Nef Inhibits Protease Activity and Its Absence Alters Protein Content of Mature Viral Particles
Nef is an important player for viral infectivity and AIDS progression, but the mechanisms involved are not completely understood. It was previously demonstrated that Nef interacts with GagPol through p6*-Protease region. Because p6* and Protease are involved in processing, we explored the effect of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991643/ https://www.ncbi.nlm.nih.gov/pubmed/24748174 http://dx.doi.org/10.1371/journal.pone.0095352 |